Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18672249 | 0.95 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL13694257 | 0.95 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL14768943 | 0.95 | NPC1 (0.52) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL15596642 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL9232300 | 0.94 | RAB9A (0.63) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL14760853 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL18672246 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL14761331 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL9233810 | 0.93 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL20159053 | 0.92 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9ANPC1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603951-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-03-28 | — | — | US | disclosed |