Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240462 | 0.94 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL10346199 | 0.93 | RAB9A (0.55) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9235695 | 0.93 | RAB9A (0.55) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9240704 | 0.93 | RAB9A (0.58) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9819418 | 0.92 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9361368 | 0.92 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9357759 | 0.92 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9361463 | 0.92 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9752441 | 0.91 | RARB (0.52) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9238778 | 0.91 | RARB (0.52) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389290-A | Ferroelectric liquid crystalline materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |