Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 7/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5106474 | 0.89 | S1PR4 (0.50) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL5623725 | 0.84 | ALDH1A1 (0.71) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL6326388 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HPGDSMN1; SMN2KDM4EPARP14 | |
| SCHEMBL18131322 | 0.81 | TDP1 (0.52) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL11187279 | 0.79 | HDAC7 (0.54) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL20893272 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL5213661 | 0.78 | ALDH1A1 (0.56) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL9233959 | 0.78 | ELANE (0.42) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL90967 | 0.77 | ALDH1A1 (0.59) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL9762630 | 0.75 | ALDH1A1 (0.57) | KMT2AALDH1A1HPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453495-A | Disazo compounds containing an optionally substituted piperazinyl group | ZENECA LIMITED (GB) | 1995-09-26 | — | — | US | disclosed |
| WO-1995017471-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |
| WO-1995017472-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |