SCHEMBL9238409

SCHEMBL9238409

O=C(c1ncc[nH]1)N1CCCC2CC=CC=C21

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 2/20 0.34
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
AXL P30530 4/20 0.32
GLA P06280 1/20 0.31
KMT2A Q03164 1/20 0.30
TYRO3 Q06418 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3306197 0.75
Hydrochloric Acid SCHEMBL11845673 0.74
SCHEMBL11142350 0.74 ALDH1A1 (0.46) SMN1; SMN2KMT2A
SCHEMBL11531912 0.70 ALDH1A1 (0.35)
SCHEMBL28065144 0.69 ALDH1A1 (0.35) SMN1; SMN2
SCHEMBL1654187 0.68 HTR2B (0.41) HTR2BHTTSMN1; SMN2GLAKMT2A
SCHEMBL9154729 0.68 KMT2A (0.42) HTTSMN1; SMN2GLAKMT2A
SCHEMBL30636902 0.65 HTT (0.50) HTR2BHTTSMN1; SMN2GLAKMT2A
SCHEMBL29098232 0.65
SCHEMBL5245434 0.65 KDM4E (0.33) SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4623377-A PREEMERGENCE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-11-18 US claimed
JP-7173137-A None JP disclosed
JP-H07173137-A TETRAHYDROQUINOLIN-1-YLCARBONYL CHLORIDE DERIVATIVE AND ITS PRODUCTION NIPPON BAYERAGROCHEM KK 1995-07-11 JP disclosed
EP-0158954-A3 TETRAHYDROQUINOLIN-1-YL CARBONYL IMIDAZOLE DERIVATIVES, THEIR INTERMEDIATES; PROCESS FOR THEIR PREPARATION AND HERBICIDES OR FUNGICIDES FOR AGRICULTURE OR HORTICULTURE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-12-03 EP disclosed
US-4623377-A PREEMERGENCE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-11-18 US disclosed
US-4623377-A PREEMERGENCE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-11-18 US disclosed
EP-0173208-A1 Tetrahydroquinolin-1-yl-carbonyl-imidazole derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-03-05 EP disclosed
EP-0173208-A1 Tetrahydroquinolin-1-yl-carbonyl-imidazole derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-03-05 EP disclosed
EP-0158954-A2 Tetrahydroquinolin-1-yl carbonyl imidazole derivatives, their intermediates; process for their preparation and herbicides or fungicides for agriculture or horticulture NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-10-23 EP disclosed