Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823983 | 1.00 | PARP1 (0.52) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8823994 | 0.82 | PARP1 (0.58) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8823991 | 0.82 | PARP1 (0.58) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8824007 | 0.79 | PARP1 (0.55) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8824011 | 0.79 | PARP1 (0.55) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL9243297 | 0.77 | PARP1 (0.53) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8828405 | 0.77 | PARP1 (0.53) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8824083 | 0.77 | PARP1 (0.48) | PARP1KCNH2GRM2KDM4EKMT2A | |
| SCHEMBL8824079 | 0.77 | PARP1 (0.48) | PARP1KCNH2GRM2KDM4EKMT2A | |
| SCHEMBL9243355 | 0.76 | PARP1 (0.55) | PARP1KCNH2GRM2HTR3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638570-A1 | TRICYCLIC COMPOUND HAVING ANTIALLERGIC EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |