Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824083 | 1.00 | PARP1 (0.48) | PARP1KCNH2GRM2HTR1AHTR2A | |
| SCHEMBL9239073 | 0.77 | PARP1 (0.52) | PARP1KCNH2GRM2ALDH1A1LMNA | |
| SCHEMBL8823994 | 0.77 | PARP1 (0.58) | PARP1KCNH2GRM2LMNAMEN1 | |
| SCHEMBL9243297 | 0.74 | PARP1 (0.53) | PARP1KCNH2GRM2LMNAMEN1 | |
| SCHEMBL9242736 | 0.73 | HTR1A (0.45) | HTR1AHTR2AHTR7HTR6ALDH1A1 | |
| SCHEMBL8824050 | 0.73 | HTR1A (0.45) | HTR1AHTR2AHTR7HTR6ALDH1A1 | |
| SCHEMBL8824023 | 0.73 | PARP1 (0.68) | PARP1KCNH2GRM2 | |
| SCHEMBL20645796 | 0.71 | ALDH1A1 (0.46) | HTR1AHTR2AHTR7HTR6ALDH1A1 | |
| SCHEMBL20640753 | 0.70 | ALDH1A1 (0.44) | HTR1AHTR2AHTR7HTR6ALDH1A1 | |
| SCHEMBL20645794 | 0.70 | ALDH1A1 (0.44) | HTR1AHTR2AHTR7HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643920-A | PYRROLO(3,2,1-IJ)QUINOLINES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0638570-A1 | TRICYCLIC COMPOUND HAVING ANTIALLERGIC EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |