Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260049 | 0.83 | CYP2D6 (0.95) | CYP2D6CYP2C19CYP1A2RECQLMEN1 | |
| SCHEMBL3207575 | 0.81 | CYP2D6 (0.97) | CYP2D6CYP2C19CYP1A2RECQLMEN1 | |
| SCHEMBL17896872 | 0.80 | HTT (0.71) | CYP2C19CYP1A2HTTALDH1A1LMNA | |
| SCHEMBL11391291 | 0.79 | HTT (1.00) | HTTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL5141415 | 0.77 | MEN1 (0.75) | CYP2D6CYP2C19CYP1A2RECQLHTT | |
| SCHEMBL18626563 | 0.77 | HTT (0.66) | HTTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3211290 | 0.77 | CYP2D6 (0.76) | CYP2D6CYP2C19CYP1A2RECQLHTT | |
| SCHEMBL17896319 | 0.77 | HTT (0.66) | HTTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL4750190 | 0.76 | CYP2D6 (0.74) | CYP2D6CYP2C19CYP1A2RECQLMEN1 | |
| SCHEMBL15092821 | 0.75 | CYP2D6 (0.76) | CYP2D6CYP2C19CYP1A2RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436301-B1 | Crystal-polymer matrix composites | BRITISH TECH GROUP (GB) | 1995-03-15 | — | — | EP | disclosed |
| US-5167888-A | In situ growth of organic and/or inorganic crystals in a polymer matrix by using temperature gradient zone melting technique | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1992-12-01 | — | — | US | disclosed |
| EP-0436301-A2 | Crystal-polymer matrix composites | BTG INTERNATIONAL LIMITED (GB) | 1991-07-10 | — | — | EP | disclosed |