Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 6/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.57 |
| ▸ | FAAH | O00519 | 4/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.48 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239190 | 1.00 | CHRNB4 (0.60) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL9242426 | 0.94 | CHRNB4 (0.67) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL4476967 | 0.94 | CHRNB4 (0.67) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL4476971 | 0.94 | CHRNB4 (0.67) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL7483954 | 0.84 | CHRNA3 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL26378415 | 0.83 | CHRNB4 (0.54) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL6184282 | 0.81 | CHRNB4 (0.48) | CHRNB4CHRNA3 | |
| SCHEMBL6191591 | 0.81 | CHRNB4 (0.48) | CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL7460326 | 0.80 | CHRNA3 (0.49) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL25594927 | 0.80 | CHRNB4 (0.51) | CHRNB4CHRNA3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | disclosed |