Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245497 | 0.95 | POLB (0.47) | POLBTSHRKDM4EATMKMT2A | |
| SCHEMBL9244809 | 0.79 | RET (0.38) | TSHRKMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL9246204 | 0.78 | BCHE (0.43) | POLBTSHRKDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9243761 | 0.77 | BCHE (0.42) | POLBTSHRKDM4EKMT2AMEN1 | |
| SCHEMBL28430986 | 0.76 | POLB (0.53) | POLBTSHRKDM4EATMKMT2A | |
| Urethane SCHEMBL28839463 | 0.75 | MAOA (0.58) | MAOAMAOBPOLBTSHRKDM4E | |
| SCHEMBL9545140 | 0.74 | POLB (0.51) | POLBTSHRKDM4EATMKMT2A | |
| SCHEMBL5552878 | 0.73 | POLB (0.50) | POLBTSHRKDM4EATMKMT2A | |
| Hydrochloric Acid SCHEMBL9241189 | 0.73 | POLB (0.50) | POLBTSHRKDM4EATMKMT2A | |
| SCHEMBL28431266 | 0.70 | SMN1; SMN2 (0.47) | POLBTSHRKDM4EATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637305-A1 | NOVEL CYCLIC AMINO ACIDS AND DERIVATIVES THEREOF | WARNER-LAMBERT COMPANY (US) | 1995-02-08 | — | — | EP | disclosed |