Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234834 | 0.85 | HDAC3 (0.37) | CYP11B1CYP11B2HDAC3HDAC6HSP90AA1 | |
| SCHEMBL6613495 | 0.84 | HDAC3 (0.40) | CYP11B1CYP11B2HDAC3HDAC6BMP1 | |
| SCHEMBL1765841 | 0.82 | CYP11B1 (0.40) | CYP11B1CYP11B2HDAC3HDAC6HSP90AA1 | |
| SCHEMBL8481796 | 0.79 | CYP11B1 (0.40) | CYP11B1CYP11B2HDAC3HDAC6HSP90AA1 | |
| SCHEMBL28067941 | 0.78 | CYP11B1 (0.42) | CYP11B1CYP11B2HDAC3HDAC6HSP90AA1 | |
| SCHEMBL27089283 | 0.77 | SMN1; SMN2 (0.36) | CYP11B1CYP11B2HDAC3HDAC6BMP1 | |
| SCHEMBL25307807 | 0.76 | CYP11B1 (0.38) | CYP11B1CYP11B2HDAC3HDAC6NR1I2 | |
| SCHEMBL27579878 | 0.76 | CYP11B1 (0.38) | CYP11B1CYP11B2HDAC3HDAC6HSP90AA1 | |
| SCHEMBL3516047 | 0.76 | CYP11B1 (0.41) | CYP11B1CYP11B2HDAC3HDAC6ALOX15 | |
| SCHEMBL9235495 | 0.75 | CYP11B1 (0.37) | CYP11B1CYP11B2HDAC3HDAC6BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675112-A1 | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |