Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240080 | 0.84 | KDM1A (0.48) | TDP1KMT2AFADS1CETPKDM4E | |
| SCHEMBL20794011 | 0.82 | HTR2B (0.47) | KMT2AFADS1DDB1CRBNHTR6 | |
| SCHEMBL13837966 | 0.82 | HTR2B (0.47) | KMT2AFADS1DDB1CRBNHTR6 | |
| SCHEMBL20780486 | 0.82 | HTR2B (0.47) | KMT2AFADS1DDB1CRBNHTR6 | |
| SCHEMBL9640635 | 0.81 | TDP1 (0.41) | TDP1DAOMEN1KMT2AALDH1A1 | |
| SCHEMBL2898141 | 0.78 | KMT2A (0.47) | KMT2AFADS1DDB1CRBNHTR6 | |
| SCHEMBL9063617 | 0.78 | F11 (0.41) | FADS1HTR6CYP19A1MAOBGRM2 | |
| SCHEMBL9063620 | 0.78 | F11 (0.41) | FADS1HTR6CYP19A1MAOBGRM2 | |
| SCHEMBL9064234 | 0.78 | F11 (0.41) | FADS1HTR6CYP19A1MAOBGRM2 | |
| SCHEMBL9671692 | 0.78 | F11 (0.41) | FADS1HTR6GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468865-A | EFFICIENCY | CELGENE CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1995029903-A1 | STEREOPREFERENTIAL SYNTHESIS OF 3-(1-PHENYLPROP-2-YL)-5-PHENYLOXAZOLIDINONES | CELGENE CORPORATION (US) | 1995-11-09 | — | — | WO | disclosed |