Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.82 |
| ▸ | RAB9A | P51151 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | GALR3 | O60755 | 1/20 | 0.82 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.82 |
| ▸ | GPR183 | P32249 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.82 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775203 | 0.94 | NPC1 (0.72) | NPC1RAB9AMEN1GALR3NR2F2 | |
| Pyridaben SCHEMBL27429 | 0.90 | MEN1 (1.00) | NPC1RAB9AMEN1GALR3NR2F2 | |
| Pyridaben SCHEMBL8372466 | 0.90 | MEN1 (1.00) | NPC1RAB9AMEN1GALR3NR2F2 | |
| SCHEMBL9775193 | 0.88 | NPC1 (0.81) | NPC1RAB9AMEN1GALR3NR2F2 | |
| SCHEMBL9775172 | 0.87 | MEN1 (0.76) | NPC1RAB9AMEN1GALR3NR2F2 | |
| SCHEMBL9238518 | 0.86 | MEN1 (0.76) | NPC1RAB9AMEN1GALR3NR2F2 | |
| SCHEMBL29458630 | 0.85 | NPC1 (0.77) | NPC1RAB9AMEN1GALR3NR2F2 | |
| SCHEMBL9234574 | 0.85 | RAB9A (0.77) | NPC1RAB9AMEN1GALR3NR2F2 | |
| SCHEMBL9775168 | 0.83 | MEN1 (0.74) | NPC1RAB9AMEN1GALR3NR2F2 | |
| SCHEMBL9238805 | 0.83 | MEN1 (0.74) | NPC1RAB9AMEN1GALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |