Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.57 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 7/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15566620 | 0.83 | CNR2 (0.59) | CNR2GRM1CNR1MITFRAB9A | |
| SCHEMBL9828687 | 0.81 | CNR2 (0.60) | CNR2GRM1CNR1MITFRAB9A | |
| SCHEMBL10670539 | 0.81 | CNR2 (0.57) | CNR2GRM1CNR1MITFRAB9A | |
| SCHEMBL26014019 | 0.78 | CNR2 (0.69) | CNR2GRM1CNR1RAB9ANPC1 | |
| SCHEMBL19000715 | 0.75 | CNR2 (0.64) | CNR2GRM1CNR1MITFRAB9A | |
| SCHEMBL14844539 | 0.74 | CNR2 (0.64) | CNR2CNR1MITFRAB9ANPC1 | |
| SCHEMBL17074594 | 0.73 | CNR2 (1.00) | CNR2GRM1CNR1RAB9AKAT2B | |
| SCHEMBL11280902 | 0.71 | CNR2 (0.47) | CNR2GRM1CNR1MITFRAB9A | |
| SCHEMBL29703260 | 0.70 | GAA (0.47) | CNR2GRM1RAB9ANPC1PDE9A | |
| SCHEMBL25355283 | 0.69 | CNR2 (0.57) | CNR2CNR1MITFRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |