Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425309 | 0.81 | GUSB (0.60) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL11112810 | 0.81 | GUSB (0.61) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL4999124 | 0.78 | GUSB (0.58) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL8980226 | 0.74 | GUSB (0.62) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL11127599 | 0.73 | GUSB (0.58) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL11490693 | 0.73 | GUSB (0.58) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL13001779 | 0.72 | CYP19A1 (1.00) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL6524579 | 0.72 | GUSB (0.60) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL12604829 | 0.72 | CYP19A1 (1.00) | GUSBCYP19A1KDM4EALDH1A1ABCB11 | |
| SCHEMBL11137065 | 0.72 | GUSB (0.60) | GUSBCYP19A1KDM4EALDH1A1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675897-A1 | NEW STEROIDS. | RHONE POULENC RORER LTD (GB) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994014834-A1 | NEW STEROIDS | RHONE-POULENC RORER LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |