SCHEMBL9240376

SCHEMBL9240376

O=P(O)(O)C(O)(CC1CCCCC1CCCS)P(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FDPS P14324 4/20 0.44
GRIN2D O15399 5/20 0.31
GRIN3B O60391 5/20 0.31
GRIN1 Q05586 5/20 0.31
GRIN2A Q12879 5/20 0.31
GRIN2B Q13224 5/20 0.31
GRIN2C Q14957 5/20 0.31
GRIN3A Q8TCU5 5/20 0.31
PDE3A Q14432 1/20 0.31
GGPS1 O95749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9166642 0.97 FDPS (0.41) FDPSPDE3AGGPS1
SCHEMBL9239082 0.87 FDPS (0.42) FDPSPDE3A
SCHEMBL9435895 0.80 FDPS (0.49) FDPSGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9241339 0.76 FDPS (0.49) FDPSPDE3AGGPS1
SCHEMBL10341443 0.73 FDPS (0.49) FDPSGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9244507 0.73 FDPS (0.45) FDPSPDE3AGGPS1
SCHEMBL19193755 0.70 FDPS (0.58) FDPSPDE3AGGPS1
SCHEMBL9166648 0.70
SCHEMBL20573016 0.69 FDPS (0.45) FDPSPDE3AGGPS1
SCHEMBL19193926 0.69 FDPS (0.56) FDPSPDE3AGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP disclosed
EP-0642519-A1 SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM PROCTER & GAMBLE PHARMACEUTICALS (US) 1995-03-15 EP disclosed
WO-1994000130-A1 COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1994-01-06 WO disclosed
WO-1993024496-A1 SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1993-12-09 WO disclosed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed