Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | FNTA | P49354 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1352739 | 0.71 | KDM4E (0.44) | ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL28585895 | 0.69 | MEN1 (0.48) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL1352274 | 0.69 | — | — | |
| SCHEMBL3943088 | 0.68 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL28594878 | 0.68 | MEN1 (0.47) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL28107053 | 0.67 | KMT2A (0.45) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL17294121 | 0.67 | FNTA (0.71) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL20434251 | 0.67 | MEN1 (0.46) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL20434250 | 0.67 | MEN1 (0.46) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL17294107 | 0.67 | FNTA (0.71) | MEN1KMT2AALDH1A1FNTAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128486-A | Sulpholenes and processes for their preparation and use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1992-07-07 | — | — | US | claimed |
| JP-7041473-A | — | — | None | — | — | JP | disclosed |
| JP-H0741473-A | NOVEL SULFOLENES, PREPARATION AND USE THEREOF | RHONE POULENC NUTRITION ANIMAL | 1995-02-10 | — | — | JP | disclosed |
| US-5128486-A | Sulpholenes and processes for their preparation and use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124499-A | Sulpholenes and processes for their preparation and use | RHONE-POULENE NUTRITION ANIMALE (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5082953-A | SULPHOLENES AND PROCESSES FOR THEIR PREPARATION AND USE | RHONE POULENC NUTRITION ANIMALE (FR) | 1992-01-21 | — | — | US | disclosed |