Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506314 | 0.86 | TRPA1 (0.54) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL21306741 | 0.86 | TRPA1 (0.67) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL25283549 | 0.86 | CYP2D6 (0.52) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL15563019 | 0.84 | TRPA1 (0.53) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL1406203 | 0.82 | TRPA1 (0.67) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL27632880 | 0.82 | CYP2D6 (0.52) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL27755423 | 0.81 | TRPA1 (0.51) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL30934 | 0.81 | TRPA1 (0.77) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL1889290 | 0.81 | TRPA1 (0.70) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL31118025 | 0.81 | CYP2D6 (0.61) | TRPA1CYP2D6SIGMAR1TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469569-B1 | Process for decabromodiphenylalkane predominant product | ALBEMARLE CORP (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5401890-A | Reducing unreacted bromine by heating | ALBEMARLE CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0460922-B1 | Decabromodiphenyl alkane process | ALBEMARLE CORP (US) | 1994-11-09 | — | — | EP | disclosed |
| EP-0447152-B1 | Decabromodiphenyl alkane process | ETHYL CORP (US) | 1994-08-03 | — | — | EP | disclosed |
| US-5302768-A | Feeding molten diphenylalkane to reaction vessel to which aluminum halide catalyst and bromine have been previously charged | ETHYL CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0347116-B1 | Process for preparing decabromodiphenylalkanes and decabromodiphenylethane. | ETHYL CORP (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5124496-A | Brominating molten diphenylalkane, treating to remove excess bromine | ETHYL CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0490378-A1 | Bromination process | ALBEMARLE CORPORATION (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0489406-A1 | Decabromodiphenylalkane process | ALBEMARLE CORPORATION (US) | 1992-06-10 | — | — | EP | disclosed |
| US-5077334-A | Flame-retarded formulations of thermoplastics and decabromodiphenylethane | ETHYL CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0460922-A1 | Decabromodiphenyl alkane process | ALBEMARLE CORPORATION (US) | 1991-12-11 | — | — | EP | disclosed |
| US-5055235-A | Heating non-condensed ring polyaromatics in the presence of bromine and a halogenation catalyst | ETHYL CORPORATION (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0447152-A1 | Decabromodiphenyl alkane process | ALBEMARLE CORPORATION (US) | 1991-09-18 | — | — | EP | disclosed |
| US-5030778-A | Decabromodiphenyl alkane process | ETHYL CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| US-5008477-A | Decabromodiphenyl alkane process | ETHYL CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0347116-A2 | Process for preparing decabromodiphenylalkanes and decabromodiphenylethane. | ETHYL CORPORATION (US) | 1989-12-20 | — | — | EP | disclosed |