SCHEMBL9242548

SCHEMBL9242548

CCCCC(C(=O)O)N1C(=O)c2ccc([Na])cc2C1=O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.53
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
ALDH1A1 P00352 2/20 0.49
CYP2D6 P10635 2/20 0.49
KDM4E B2RXH2 1/20 0.49
TP53 P04637 1/20 0.49
GLA P06280 1/20 0.49
POLB P06746 1/20 0.49
CYP3A4 P08684 1/20 0.49
HPGD P15428 1/20 0.49
ALOX12 P18054 1/20 0.49
NFKB1 P19838 1/20 0.49
APEX1 P27695 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GAA P10253 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133528 0.84 POLB (0.68) MAPK1KMT2AALDH1A1CYP2D6KDM4E
SCHEMBL29783279 0.84 POLB (0.68) MAPK1KMT2AALDH1A1CYP2D6KDM4E
SCHEMBL5864490 0.84 MAPK1 (0.70) MAPK1MEN1KMT2ACYP2D6POLB
Hydrochloric Acid SCHEMBL7757351 0.83 POLB (0.66) MAPK1KMT2AALDH1A1CYP2D6KDM4E
Hydrochloric Acid SCHEMBL8187825 0.83 POLB (0.66) MAPK1KMT2AALDH1A1CYP2D6KDM4E
SCHEMBL28775935 0.80 POLB (0.66) MAPK1KMT2AALDH1A1CYP2D6KDM4E
SCHEMBL15502146 0.79 MAPK1 (0.67) MAPK1MEN1KMT2ACYP2D6POLB
SCHEMBL28775906 0.79 POLB (0.64) MAPK1KMT2AALDH1A1CYP2D6KDM4E
SCHEMBL9899331 0.79 POLB (0.64) MAPK1KMT2AALDH1A1CYP2D6KDM4E
SCHEMBL31661829 0.79 POLB (0.64) MAPK1KMT2AALDH1A1CYP2D6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0183493-B2 Modified ethylenic random copolymer MITSUI PETROCHEMICAL IND (JP) 1995-05-24 EP disclosed
US-5093418-A Grafted with unsaturated acid, ester, anhydride, vinylaromatic or unsaturated silane compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-03-03 US disclosed
EP-0183493-B1 MODIFIED ETHYLENIC RANDOM COPOLYMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-09-19 EP disclosed
US-4908411-A Ethylene, alpha olefin, grafted thereto unsaturated carboxylic acid, styrene hydrocarbon, unsaturated silane compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-13 US disclosed
EP-0183493-A2 Modified ethylenic random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-06-04 EP disclosed