Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520560 | 0.94 | RAB9A (0.50) | NPC1RAB9AL3MBTL1LMNAMAPK1 | |
| SCHEMBL11536530 | 0.92 | ADORA2A (0.51) | NPC1RAB9AL3MBTL1LMNAMAPK1 | |
| SCHEMBL14489850 | 0.89 | AKR1C3 (0.47) | NPC1RAB9AL3MBTL1LMNAMAPK1 | |
| SCHEMBL13962363 | 0.88 | AKR1C3 (0.48) | NPC1RAB9AMAPK1MEN1MAPT | |
| SCHEMBL28543816 | 0.87 | MAPT (0.49) | NPC1RAB9AL3MBTL1LMNAMAPK1 | |
| SCHEMBL11602174 | 0.83 | MAPK1 (0.46) | NPC1RAB9AL3MBTL1LMNAMAPK1 | |
| SCHEMBL35556 | 0.81 | P2RY2 (0.60) | NPC1RAB9AL3MBTL1LMNAMAPK1 | |
| SCHEMBL29352213 | 0.81 | P2RY2 (0.60) | NPC1RAB9AL3MBTL1LMNAMAPK1 | |
| SCHEMBL11605977 | 0.81 | P2RY12 (0.57) | NPC1RAB9AL3MBTL1LMNAMAPK1 | |
| SCHEMBL595104 | 0.81 | P2RY12 (0.56) | NPC1RAB9AL3MBTL1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370316-B1 | Cooling oil based on siloxane | BAYER AG (DE) | 1995-01-04 | — | — | EP | disclosed |
| US-5332521-A | Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device | IDEMITSU KOSAN CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0352637-B1 | Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device | IDEMITSU KOSAN CO (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-5273670-A | Octamethyltrisiloxane and octamethylcyclotetrasiloxane decamethylcyclopentasiloxane; low temperatures of-86 C. to -130 C. | BAYER AG (DE) | 1993-12-28 | — | — | US | disclosed |
| US-5200108-A | Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer | IDEMITSU KOSAN CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0396971-A2 | Stabilized polydiorganosiloxanes and their use in hydraulic applications | BAYER AG (DE) | 1990-11-14 | — | — | EP | disclosed |
| EP-0370316-A1 | Cooling oil based on siloxane | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |
| EP-0352637-A2 | Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-01-31 | — | — | EP | disclosed |
| EP-0244617-A1 | Age-resisting polysiloxanes | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |