Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | PRKACA | P17612 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | MARK3 | P27448 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 3/20 | 0.38 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL923645 | 0.87 | TRPA1 (0.41) | TRPA1ROCK2ROCK1GSK3BCDK5 | |
| SCHEMBL3882183 | 0.87 | TRPA1 (0.45) | TRPA1ROCK2ROCK1GSK3BCDK5 | |
| SCHEMBL3891750 | 0.84 | TRPA1 (0.38) | TRPA1ROCK2ROCK1GSK3BCDK5 | |
| SCHEMBL3891742 | 0.84 | TRPA1 (0.38) | TRPA1ROCK2ROCK1GSK3BCDK5 | |
| SCHEMBL924797 | 0.83 | AR (0.44) | TRPA1 | |
| SCHEMBL3882061 | 0.83 | FFAR4 (0.45) | TRPA1ROCK2ROCK1GSK3BCDK5 | |
| SCHEMBL923097 | 0.82 | RAD51 (0.37) | — | |
| SCHEMBL3884737 | 0.81 | TRPA1 (0.41) | TRPA1MAPK14ROCK2ROCK1GSK3B | |
| SCHEMBL922867 | 0.79 | USP7 (0.36) | TRPA1MAPK14ROCK2GSK3BCDK5 | |
| SCHEMBL923774 | 0.79 | ABCB1 (0.42) | TRPA1MAPK14ROCK2CPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620431-A1 | Novel crystals of substituted phenylalkanoic acid and production process | Asahi Kasei Pharma Corporation (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-2045244-B1 | NOVEL CRYSTAL OF SUBSTITUTED PHENYLALKANOIC ACID AND PRODUCTION PROCESS | ASAHI KASEI PHARMA CORP (JP) | 2013-04-03 | — | — | EP | disclosed |
| US-7935720-B2 | Crystal of substituted phenylalkanoic acid ester and process for producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2011-05-03 | — | — | US | disclosed |
| US-20110021593-A1 | NOVEL CRYSTAL OF SUBSTITUTED PHENYLALKANOIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME | SHODA MOTOSHI | 2011-01-27 | — | — | US | disclosed |
| US-7838546-B2 | Crystal of substituted phenylalkanoic acid ester and process for producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20100234440-A1 | NOVEL CRYSTAL OF SUBSTITUTED PHENYLALKANOIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME | SHODA MOTOSHI | 2010-09-16 | — | — | US | disclosed |
| US-7754752-B2 | Crystals of substituted phenylalkanoic acid and method of producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20090312386-A1 | NOVEL CRYSTALS OF SUBSTITUTED PHENYLALKANOIC ACID AND METHOD OF PRODUCING THE SAME | ARIMOTO YUICHI | 2009-12-17 | — | — | US | disclosed |
| US-7560478-B2 | Crystal forms of substituted phenylalkanoic acids and process for producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-07-14 | — | — | US | disclosed |
| EP-2045244-A1 | NOVEL CRYSTAL OF SUBSTITUTED PHENYLALKANOIC ACID AND PRODUCTION PROCESS | Asahi Kasei Pharma Corporation (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-20080070967-A1 | Novel crystal forms of substituted phenylalkanoic acids and process for producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2008-03-20 | — | — | US | disclosed |