SCHEMBL924323

SCHEMBL924323

FC(F)n1cccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28775806 0.91 NOS1 (0.35)
SCHEMBL7063305 0.79
SCHEMBL28778425 0.79
SCHEMBL737313 0.77 NOS1 (0.33)
SCHEMBL23873160 0.75 TSHR (0.32)
SCHEMBL2362852 0.75
SCHEMBL31010130 0.74
SCHEMBL15467987 0.74
SCHEMBL28015823 0.74
SCHEMBL2575521 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
US-20240174679-A1 HETEROAROYL AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2024-05-30 US claimed
EP-4127157-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-02-08 EP claimed
EP-4103553-A1 NEW PROCESS FOR THE SYNTHESIS OF 5-FLUORO-3- (DIFUOROMETHYL) -5-FLUORO-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES AND THE FREE ACID THEREOF Fujian Yongjing Technology Co., Ltd (CN) 2022-12-21 EP claimed
US-20220372000-A1 New Process for the Synthesis of 5-Fluoro-3-(Difuoromethyl)-5-Fluoro-1-Methyl-1H-Pyrazole-4-Carboxylic Acid Derivatives and the Free Acid Thereof Fujian Yongjing Technology Co.,Ltd (CN) 2022-11-24 US claimed
CN-114829360-A Process for the preparation of [ 3-chloro-2- [3- [2- [1- (2-chloroacetyl) -4-piperidinyl ] thiazol-4-yl ] -4, 5-dihydroisoxazol-5-yl ] phenyl ] methanesulfonate 拜耳公司 2022-07-29 CN claimed
CN-114450269-A Novel method for synthesizing 5-fluoro-3- (difluoromethyl) -5-fluoro-1-methyl-1H-pyrazole-4-carboxylic acid derivative and free acid thereof 福建永晶科技股份有限公司 2022-05-06 CN claimed
WO-2022072560-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2022-04-07 WO claimed
CN-111320621-A Indolizine compound and preparation method and application thereof 中国科学院广州生物医药与健康研究院 2020-06-23 CN claimed
WO-2019197615-A1 ACTIVE INGREDIENT COMBINATIONS WITH FUNGICIDES, INSECTICIDES AND ACARICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO claimed
CN-107427001-A Fungicidal active substance combinations 拜耳作物科学股份公司 2017-12-01 CN claimed
EP-0731793-A1 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION G.D. SEARLE &amp; CO. (US) 1996-09-18 EP claimed
WO-1995015315-A1 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-06-08 WO claimed
US-20260138982-A1 Biaryl Acid Compounds PFIZER INC (US) 2026-05-21 US disclosed
WO-2026107422-A1 6-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE DERIVATIVES AS CAMK2 INHIBITORS FOR THE TREATMENT OF HEART FAILURE BRISTOL-MYERS SQUIBB COMPANY (US) 2026-05-21 WO disclosed
US-20260132109-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2026-05-14 US disclosed
WO-1996033717-A1 THERAPEUTIC COMPOSITION FOR ARTHRITIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-10-31 WO disclosed
EP-0731793-A1 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION G.D. SEARLE &amp; CO. (US) 1996-09-18 EP disclosed
WO-1996003385-A1 3,4-SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-02-08 WO disclosed
WO-1995015315-A1 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-06-08 WO disclosed