Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 12/20 | 0.61 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642238 | 0.89 | HTR1B (0.69) | HTR1BKCNA3HTR1DALDH1A1MEN1 | |
| SCHEMBL8674828 | 0.89 | HTR1B (0.69) | HTR1BKCNA3HTR1DALDH1A1MEN1 | |
| SCHEMBL5289923 | 0.87 | HTR1B (0.77) | HTR1BKCNA3HTR1DALDH1A1MEN1 | |
| SCHEMBL8675367 | 0.85 | HTR1B (0.65) | HTR1BKCNA3HTR1DALDH1A1MEN1 | |
| SCHEMBL68267 | 0.83 | HTR1B (0.67) | HTR1BKCNA3HTR1DALDH1A1MEN1 | |
| SCHEMBL240439 | 0.83 | HTR1B (0.60) | HTR1BKCNA3HTR1DALDH1A1MEN1 | |
| SCHEMBL15295198 | 0.82 | HTR1B (0.71) | HTR1BKCNA3HTR1DALDH1A1MEN1 | |
| SCHEMBL4059998 | 0.82 | HTR1B (0.61) | HTR1BKCNA3HTR1DALDH1A1MEN1 | |
| SCHEMBL97164 | 0.81 | HTR1B (0.68) | HTR1BKCNA3HTR1DKMT2ASLC6A4 | |
| SCHEMBL27421928 | 0.81 | HTR1B (0.56) | HTR1BKCNA3HTR1DALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447900-A | Fluoran leuco dye and developer | RICOH COMPANY, LTD. (JP) | 1995-09-05 | — | — | US | disclosed |