Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198618 | 0.90 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL332972 | 0.82 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9174637 | 0.82 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL13197625 | 0.81 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9292323 | 0.79 | TSHR (0.47) | TSHRALDH1A1THRB | |
| SCHEMBL3113881 | 0.79 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18504299 | 0.78 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL16488937 | 0.78 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29042636 | 0.76 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL231327 | 0.76 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219312-B1 | Improved fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORP (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0424099-B1 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORP (US) | 1995-10-04 | — | — | EP | disclosed |
| US-5346978-A | Polymeric compositions useful in oxygen permeable contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5177168-A | Copolymer of an unsaturated carboxylic acid ester | POLYMER TECHNOLOGY CORP. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5032658-A | Hardness, unsaturated ester | POLYMER TECHNOLOGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0424099-A2 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4996275-A | With silicon group-substituted addition polymers; oxygen permeability, hydrophilic, deposit resistance | POLYMER TECHNOLOGY CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |
| US-4686267-A | Fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1987-08-11 | — | — | US | disclosed |
| EP-0219312-A2 | Improved fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1987-04-22 | — | — | EP | disclosed |