SCHEMBL332972

SCHEMBL332972

C=CC(=O)OC[Si](C)(C)O[Si](C)(C)COC(=O)C=C

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.47
HPGD P15428 1/20 0.45
ALDH1A1 P00352 6/20 0.45
TP53 P04637 3/20 0.45
HIF1A Q16665 3/20 0.45
CYP3A4 P08684 2/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
THRB P10828 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29042636 0.92 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL14198618 0.92 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3113881 0.92 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL13197625 0.87 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1010877 0.87 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL107384 0.85 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5069823 0.85 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9174637 0.84 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9243728 0.82 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL600138 0.82 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049184-A1 CURABLE COMPOSITION AND INK FOR INK-JET PRINTING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-02-19 US disclosed
US-20240301142-A1 ORGANOPOLYSILOXANE AND PRODUCTION METHOD THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-09-12 US disclosed
EP-4368658-A1 ORGANOPOLYSILOXANE AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-15 EP disclosed
CN-117616068-A Organopolysiloxane and method for producing same 信越化学工业株式会社 2024-02-27 CN disclosed
WO-2023282115-A1 ORGANOPOLYSILOXANE AND PRODUCTION METHOD THEREFOR 信越化学工業株式会社 2023-01-12 WO disclosed
EP-4089147-A1 CURABLE COMPOSITION AND INK FOR INK-JET PRINTING Shin-Etsu Chemical Co., Ltd. (JP) 2022-11-16 EP disclosed
US-10233322-B2 UV-curable organopolysiloxane composition, silicone gel cured product, and pressure sensor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-03-19 US disclosed
EP-2321123-B1 METALLIZED PARTICLES FORMED FROM A DISPERSION DOW SILICONES CORP (US) 2018-08-08 EP disclosed
EP-2490663-B1 SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL DOW CORNING (US) 2017-09-20 EP disclosed
EP-2995650-B1 UV-CURABLE ORGANOPOLYSILOXANE COMPOSITION, SILICONE GEL CURED PRODUCT, AND PRESSURE SENSOR SHINETSU CHEMICAL CO (JP) 2017-04-19 EP disclosed
US-20090306307-A1 Curable Organosilicon Composition DOW SILICONES CORPORATION 2009-12-10 US disclosed
US-7241823-B2 Radiation curing silicone rubber composition, adhesive silicone elastomer film formed from same, semiconductor device using same, and method of producing semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-07-10 US disclosed
EP-0970978-B1 Radiation-curable liquid resin composition suitable for coating optical fibers and optical fiber coated therewith SHINETSU CHEMICAL CO (JP) 2004-09-22 EP disclosed
US-20040127613-A1 Radiation curing silicone rubber composition, adhesive silicone elastomer film formed from same, semiconductor device using same, and method of producing semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-07-01 US disclosed
EP-0685506-B1 Method for the preparation of (meth)acryloxyalkyl group-containing linear organopolysiloxane SHINETSU CHEMICAL CO (JP) 2002-04-03 EP disclosed
US-6248803-B1 ACRYLATED POLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-06-19 US disclosed
US-6198867-B1 POLYSILOXANE ENDCAPPED WITH (METH)ACRYL GROUP, AND CONTAINING AROMATIC HYDROCARBON GROUPS ATTACHED TO SILICON ATOMS, AN UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION CATALYST; LOW VISCOSITY, CURES TO A LOW YOUNG'S MODULUS COATING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-03-06 US disclosed
EP-0970978-A1 Radiation-curable liquid resin composition suitable for coating optical fibers and optical fiber coated therewith SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-01-12 EP disclosed
US-5504234-A MIXING CYCLIC POLYSILOXANE OLIGOMER HAVING ACRYLOXYALKYL GROUP WITH CATION EXCHANGE RESIN, HEATING TO EFFECT RING-OPENING SILOXANE REARRANGEMENT POLYMERIZATION, REMOVING RESIN SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-04-02 US disclosed
EP-0685506-A2 Method for the preparation of (meth)acryloxyalkyl group-containing linear organopolysiloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049184-A1 CURABLE COMPOSITION AND INK FOR INK-JET PRINTING SEM1, COL1A1, HTR3D TSHR 3974/4885HPGD 3457/4885ALDH1A1 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.