Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.67 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.67 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.67 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | RNF4 | P78317 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17272756 | 0.87 | PDK1 (0.70) | PDK1PDK2PDK3PDK4HDAC1 | |
| SCHEMBL6928414 | 0.80 | HPGD (0.67) | PDK1PDK2PDK3PDK4HPGD | |
| SCHEMBL14253966 | 0.80 | PDK1 (0.70) | PDK1PDK2PDK3PDK4HPGD | |
| SCHEMBL30249298 | 0.80 | HDAC1 (0.70) | PDK1PDK2PDK3PDK4HDAC1 | |
| SCHEMBL8846991 | 0.78 | HDAC1 (0.72) | PDK1PDK2PDK3PDK4HDAC1 | |
| SCHEMBL4653369 | 0.77 | HPGD (0.70) | HPGDSMN1; SMN2PGRTGM2RNF4 | |
| SCHEMBL30053559 | 0.77 | CA12 (0.73) | HPGDSMN1; SMN2PGRTGM2RNF4 | |
| SCHEMBL4265086 | 0.76 | EPHX2 (0.69) | PDK1PDK2PDK3PDK4HPGD | |
| SCHEMBL21295380 | 0.75 | CA12 (0.71) | HPGDSMN1; SMN2PGRTGM2RNF4 | |
| SCHEMBL2887967 | 0.75 | HDAC1 (0.78) | PDK1PDK2PDK3PDK4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436310-A | Aromatic polymers | RAYCHEM CORPORATION (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0178185-B1 | NOVEL AROMATIC POLYMERS | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4868271-A | POLYETHER KETONES | RAYCHEM CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| WO-1986002368-A1 | AROMATIC POLY(ETHER KETONES) HAVING IMIDE, AMIDE, ESTER, AZO, QUINOXALINE, BENZIMIDAZOLE, BENZOXAZOLE OR BENZOTHIAZOLE GROUPS AND METHOD OF PREPARATION | RAYCHEM CORPORATION (US) | 1986-04-24 | — | — | WO | disclosed |
| EP-0178185-A2 | Novel aromatic polymers | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | disclosed |