⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244386 | 1.00 | — | — | |
| SCHEMBL6206227 | 1.00 | — | — | |
| SCHEMBL28033635 | 0.91 | — | — | |
| SCHEMBL22323577 | 0.91 | — | — | |
| SCHEMBL23871232 | 0.88 | FAAH (0.38) | — | |
| SCHEMBL5853426 | 0.88 | FAAH (0.38) | — | |
| SCHEMBL5852731 | 0.88 | FAAH (0.38) | — | |
| SCHEMBL3359378 | 0.88 | FAAH (0.38) | — | |
| SCHEMBL5853430 | 0.88 | FAAH (0.38) | — | |
| SCHEMBL5852727 | 0.88 | FAAH (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017031209-A1 | TUBULYSIN ANALOGS AND METHODS | ENDOCYTE, INC. (US) | 2017-02-23 | — | — | WO | claimed |
| US-3981920-A | Method for preparing cyclopentenone derivatives | FIRMENICH S.A. (CH) | 1976-09-21 | — | — | US | claimed |
| US-11952438-B2 | 1,3-dipolar compound comprising an epoxide group | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2024-04-09 | — | — | US | disclosed |
| CN-111372923-B | 1, 3-dipolar compounds comprising epoxy groups | 米其林集团总公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20230135152-A1 | PIKFYVE KINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-04 | — | — | US | disclosed |
| EP-3713924-B1 | 1,3-DIPOLAR COMPOUND COMPRISING AN EPOXIDE GROUP | MICHELIN & CIE (FR) | 2023-01-04 | — | — | EP | disclosed |
| EP-3713924-B1 | 1,3-DIPOLAR COMPOUND COMPRISING AN EPOXIDE GROUP | MICHELIN & CIE (FR) | 2023-01-04 | — | — | EP | disclosed |
| US-11492459-B2 | Rubber composition | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2022-11-08 | — | — | US | disclosed |
| CN-111372790-B | Diene polymers modified by epoxide groups | 米其林集团总公司 | 2022-06-21 | — | — | CN | disclosed |
| EP-3713774-B1 | RUBBER COMPOSITION | MICHELIN & CIE (FR) | 2022-03-09 | — | — | EP | disclosed |
| US-20210171669-A1 | DIENE POLYMER MODIFIED BY AN EPOXIDE GROUP | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-06-10 | — | — | US | disclosed |
| WO-2019102128-A1 | 1,3-DIPOLAR COMPOUND COMPRISING AN EPOXIDE GROUP | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019102131-A1 | RUBBER COMPOSITION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2019-05-31 | — | — | WO | disclosed |
| WO-2017031209-A1 | TUBULYSIN ANALOGS AND METHODS | ENDOCYTE, INC. (US) | 2017-02-23 | — | — | WO | disclosed |
| CN-101514216-B | Synthesis method of saffron glucoside | UNIV SICHUAN | 2012-05-23 | — | — | CN | disclosed |
| CN-101514216-A | Method for synthesizing crocin glucoside | UNIV SICHUAN (CN) | 2009-08-26 | — | — | CN | disclosed |
| EP-0410742-B1 | Phenylethenyl compounds having retinoid-like activity | ALLERGAN INC (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5068252-A | Acids, esters, amides, alcohol and ether derivatives | ALLERGAN, INC. (US) | 1991-11-26 | — | — | US | disclosed |
| US-4992468-A | Treatment of skin disorders | ALLERGAN, INC. (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0410742-A1 | Phenylethenyl compounds having retinoid-like activity | ALLERGAN, INC. (US) | 1991-01-30 | — | — | EP | disclosed |