SCHEMBL92444

SCHEMBL92444

CCOC(=O)c1ccc(-n2nc(C(C)(C)C)c(N=Nc3ccc([N+](=O)[O-])cc3)c2N)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.51
PTPN1 P18031 1/20 0.50
PTPN6 P29350 1/20 0.50
PTPN11 Q06124 1/20 0.50
HTT P42858 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
KCNJ1 P48048 1/20 0.45
KCNH2 Q12809 1/20 0.45
CCNE1 P24864 1/20 0.44
CDK2 P24941 1/20 0.44
ADORA1 P30542 1/20 0.44
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.43
CA9 Q16790 1/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
SLC5A1 P13866 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92457 0.82 ALOX5 (0.52) MAPTPTPN1PTPN6PTPN11HTT
SCHEMBL91890 0.82 SMN1; SMN2 (0.51) MAPTPTPN1PTPN6PTPN11HTT
SCHEMBL2623686 0.82 SMN1; SMN2 (0.51) MAPTPTPN1PTPN6PTPN11HTT
SCHEMBL12636751 0.82 AR (0.44) MAPTPTPN1HTTL3MBTL1ADORA1
SCHEMBL14280348 0.75 CCNE1 (0.45) MAPTHTTCCNE1CDK2ALDH1A1
SCHEMBL92445 0.74 CCNE1 (0.48) MAPTHTTCCNE1CDK2ALDH1A1
SCHEMBL14280341 0.74 CCNE1 (0.44) MAPTHTTL3MBTL1CCNE1CDK2
SCHEMBL92469 0.72 MEN1 (0.45) MAPTPTPN1PTPN6PTPN11HTT
SCHEMBL14280346 0.72 CCNE1 (0.42) MAPTHTTCCNE1CDK2ALDH1A1
SCHEMBL14280342 0.72 CCNE1 (0.42) MAPTHTTCCNE1CDK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129309-B2 Multilayer; substrate with at least three heat sensitive transfer sheets containing dyes and resins, heat resistant slipping layers; containing polyvinyl butyral and polyvinyl acetate FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8119562-B2 Heat-sensitive transfer sheet and image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8067336-B2 Polyethylene innermost surface layer FUJIFILM CORPORATION (JP) 2011-11-29 US disclosed
US-8017552-B2 Has thermal transfer layer on a support, can stably keep up good capability of peeling off an image-receiving sheet without being affected by properties of a support, running stability FUJIFILM CORPORATION (JP) 2011-09-13 US disclosed
US-8012909-B2 Receiver sheet includes receptor layer containing yellow, cyan, magenta dyes; superimposing heat sensitive transfer sheet ; heating; process control FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7932210-B2 Image-forming method using thermal transfer system FUJIFILM CORPORATION (JP) 2011-04-26 US disclosed
US-7879524-B2 Heat sensitive transfer image receiver sheet and heat sensitive transfer sheet on support; dye receiver layer; heat insulation layer containing hollow polymer particles and hydrophilic polymer FUJIFILM CORPORATION (JP) 2011-02-01 US disclosed
US-20090196141-A1 OPTICAL RECORDING MEDIUM, METHOD FOR UTILIZING DYE COMPOUND AND VISIBLE INFORMATION RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 US disclosed
US-20080287291-A1 HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080274881-A1 THERMOSENSITIVE TRANSFER INK SHEET, AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080274880-A1 HEAT-SENSITIVE TRANSFER SHEET FOR USE IN HEAT-SENSITIVE TRANSFER SYSTEM AND IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080269048-A1 CARDBOARD CYLINDER FOR A HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET, ROLLED HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET TO FORM A ROLL SHAPE, AND IMAGE-FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-20080254383-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080254981-A1 HEAT-SENSITIVE TRANSFER IMAGE-FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080248949-A1 HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMATION METHOD FUJIFILM CORPORATION (JP) 2008-10-09 US disclosed
US-20080081766-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
US-20070213217-A1 Image-forming method using thermal transfer system FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed