SCHEMBL9244647

SCHEMBL9244647

CCC(C)OC(=O)CC(O)(CC(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.41
KDM4E B2RXH2 4/20 0.40
LMNA P02545 3/20 0.40
TSHR P16473 2/20 0.40
ALOX15 P16050 1/20 0.40
CYP2D6 P10635 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC13A5 Q86YT5 8/20 0.34
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
EPHX2 P34913 1/20 0.32
CPT2 P23786 1/20 0.32
ACLY P53396 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244620 0.95 ALDH1A1 (0.41) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL9244610 0.88 ALDH1A1 (0.36) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL4339036 0.87 ALDH1A1 (0.48) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL29124823 0.86 ALDH1A1 (0.52) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL489812 0.86 ALDH1A1 (0.52) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL27805119 0.85 ALDH1A1 (0.50) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL2831494 0.84 ALDH1A1 (0.54) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL37069 0.84 ALDH1A1 (0.58) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL428393 0.83 ALDH1A1 (0.48) ALDH1A1MAPTKDM4ELMNATSHR
SCHEMBL26073614 0.83 ALDH1A1 (0.44) ALDH1A1MAPTKDM4ELMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5391771-A Reacting citric acid or esters on hydrogenation catalyst in nonaqueous solvent BASF AKTIENGESELLSCHAFT 1995-02-21 US disclosed