SCHEMBL9244707

SCHEMBL9244707

COC(=O)CCON1C(C)(C)CC(c2ccc(C(=O)O)c(C(=O)O)c2C2CC(C)(C)N(OCCC(=O)OC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9374760 0.93 NPC1 (0.31) NPC1MEN1GAAKMT2A
SCHEMBL9871097 0.85 CNR1 (0.34) NPC1
SCHEMBL9736787 0.79 TSHR (0.45) MEN1GAAKMT2A
SCHEMBL317241 0.77 GAA (0.34) GAAKMT2A
SCHEMBL9738159 0.77 ACHE (0.37)
SCHEMBL9739312 0.76 TSHR (0.33) MEN1KMT2A
SCHEMBL9589144 0.75 MAPT (0.30)
SCHEMBL9589149 0.75 MAPT (0.30)
SCHEMBL11287699 0.75 ESR1 (0.33)
SCHEMBL9576869 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467850-B1 Stabilized monomer compositions CIBA GEIGY AG (CH) 1995-09-06 EP claimed
EP-0389422-B1 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-5015678-A Light stabilized polymers by the addition of N-hydoxyamines CIBA-GEIGY CORPORATION (US) 1991-05-14 US claimed