Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.81 |
| ▸ | NAT1 | P18440 | 1/20 | 0.70 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.65 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.65 |
| ▸ | CLK1 | P49759 | 1/20 | 0.65 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.65 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245206 | 1.00 | CA2 (0.81) | CA2NAT1CISD1MAOBDYRK1A | |
| SCHEMBL6638503 | 0.90 | CA2 (1.00) | CA2NAT1CISD1MAOBDYRK1A | |
| SCHEMBL6638506 | 0.90 | CA2 (1.00) | CA2NAT1CISD1MAOBDYRK1A | |
| SCHEMBL8310039 | 0.90 | CA2 (1.00) | CA2NAT1CISD1MAOBDYRK1A | |
| SCHEMBL4803625 | 0.87 | CA2 (0.73) | CA2NAT1CISD1MAOBDYRK1A | |
| SCHEMBL4803620 | 0.87 | CA2 (0.73) | CA2NAT1CISD1MAOBDYRK1A | |
| SCHEMBL15091371 | 0.86 | GSK3B (0.70) | CA2DYRK1ACSNK2A1PDE4BMEN1 | |
| SCHEMBL15101838 | 0.86 | GSK3B (0.70) | CA2DYRK1ACSNK2A1PDE4BMEN1 | |
| SCHEMBL18102869 | 0.86 | CISD1 (0.71) | CA2NAT1CISD1MAOBDYRK1A | |
| SCHEMBL7558738 | 0.86 | CA2 (0.71) | CA2NAT1CISD1MAOBDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2062864-A | — | — | None | — | — | JP | disclosed |
| US-5464856-A | Arylmethylenyl derivatives of imidazolidinones useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5306822-A | Mono-, di- or tri-methoxyphenylmethylene-2-thioxo-4-oxazolidinone as antihistamines | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5208250-A | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| JP-H0262864-A | DRUG COMPOSITION FOR THERAPY OF ALLERGY AND INFLAMMATION | WARNER LAMBERT CO | 1990-03-02 | — | — | JP | disclosed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |