Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647531 | 1.00 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9249624 | 0.85 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9249618 | 0.85 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9242896 | 0.84 | MAPT (0.35) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9242891 | 0.84 | MAPT (0.35) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9242889 | 0.84 | MAPT (0.35) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9249698 | 0.83 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9249694 | 0.83 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9249700 | 0.83 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9646706 | 0.82 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346107-B1 | Arylfluoroalkenamides and their use as pesticides | ROUSSEL UCLAF (FR) | 1995-09-13 | — | — | EP | disclosed |
| US-5114940-A | Insecticides or anthelmintics from fused ring heterocycles containing amides or thioamides | ROUSSEL-UCLAF (FR) | 1992-05-19 | — | — | US | disclosed |