SCHEMBL9245802

SCHEMBL9245802

CCCCOC(F)(C(O)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES1 P23141 9/20 0.41
CES2 O00748 1/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
ATM Q13315 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17553325 0.86 ADRB2 (0.38) CES1CES2TSHRALDH1A1ADRB2
Tetramethylammonium Ion SCHEMBL28622319 0.81 CES1 (0.32) CES1
SCHEMBL14691718 0.79 CES1 (0.45) CES1CES2TSHRFAAH
SCHEMBL9588545 0.76 CES1 (0.47) CES1CES2TSHRFAAH
SCHEMBL7565286 0.74 CES1 (0.37) CES1CES2TSHRALDH1A1ADRB2
SCHEMBL7558018 0.72 CES1 (0.36) CES1CES2TSHRALDH1A1ADRB2
SCHEMBL2813689 0.72 ADRB2 (0.38) CES1CES2TSHRALDH1A1ADRB2
SCHEMBL20583956 0.71 CES1 (0.35) CES1CES2TSHRALDH1A1ADRB2
SCHEMBL17676637 0.71 CES1 (0.31) CES1
SCHEMBL3360881 0.71 TSHR (0.42) CES1TSHRALDH1A1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597887-B1 FLUORINE-CONTAINING PLASTIC OPTICAL FIBER CORES MINNESOTA MINING & MFG (US) 1995-08-30 EP disclosed
US-5223593-A Low optical loss; dihydroperfluoroacrylate polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-29 US disclosed