Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251354 | 0.92 | SIRT2 (0.53) | ATMTP53MAPTKMT2AHPGD | |
| SCHEMBL9254349 | 0.91 | ATM (0.58) | ATMTP53MAPTKMT2AHPGD | |
| SCHEMBL9249697 | 0.90 | KMT2A (0.47) | ATMTP53MAPTKMT2AHPGD | |
| SCHEMBL9248757 | 0.90 | KMT2A (0.47) | ATMTP53MAPTKMT2AHPGD | |
| SCHEMBL9245332 | 0.89 | KMT2A (0.46) | ATMTP53MAPTKMT2AHPGD | |
| SCHEMBL9255089 | 0.88 | KMT2A (0.45) | ATMTP53MAPTKMT2AHPGD | |
| SCHEMBL9247672 | 0.87 | KMT2A (0.49) | ATMTP53MAPTKMT2AHPGD | |
| SCHEMBL9254808 | 0.87 | HPGD (0.49) | TP53MAPTKMT2AHPGDMEN1 | |
| SCHEMBL8863519 | 0.84 | HDAC1 (0.52) | TP53MAPTKMT2AHPGDLMNA | |
| Hydrochloric Acid SCHEMBL9255053 | 0.83 | HDAC1 (0.51) | TP53MAPTKMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |