Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251899 | 0.93 | HPGD (0.49) | HPGDHSD17B10ALDH1A1MAPK1THRB | |
| SCHEMBL9247672 | 0.91 | KMT2A (0.49) | HPGDHSD17B10ALDH1A1MAPK1MAPT | |
| SCHEMBL9251354 | 0.91 | SIRT2 (0.53) | HPGDHSD17B10MAPTPOLBKMT2A | |
| SCHEMBL9245997 | 0.87 | ATM (0.57) | HPGDMAPTKMT2ATDP1MEN1 | |
| SCHEMBL9255089 | 0.86 | KMT2A (0.45) | HPGDMAPTPOLBKMT2ATDP1 | |
| SCHEMBL8863519 | 0.85 | HDAC1 (0.52) | HPGDSMN1; SMN2MAPTKMT2ATDP1 | |
| SCHEMBL9249697 | 0.84 | KMT2A (0.47) | HPGDMAPTPOLBKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL9255053 | 0.84 | HDAC1 (0.51) | HPGDSMN1; SMN2MAPTKMT2ATDP1 | |
| SCHEMBL9248757 | 0.84 | KMT2A (0.47) | HPGDHSD17B10ALDH1A1MAPTPOLB | |
| SCHEMBL9245332 | 0.83 | KMT2A (0.46) | HPGDMAPTPOLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |