SCHEMBL9246348

SCHEMBL9246348

C=CCc1ccc(C(=O)O)c(O)c1.[Zn]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.59
ALDH1A1 P00352 4/20 0.53
MAPT P10636 4/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
GAA P10253 3/20 0.53
GABRA1 P14867 3/20 0.53
GABRB2 P47870 3/20 0.53
KDM4E B2RXH2 2/20 0.53
CNR1 P21554 2/20 0.53
CNR2 P34972 2/20 0.53
ALDH2 P05091 1/20 0.53
AKR1B1 P15121 1/20 0.53
HPGD P15428 1/20 0.53
PPARG P37231 1/20 0.53
PPARD Q03181 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
PPARA Q07869 1/20 0.50
TNKS O95271 1/20 0.49
PARP1 P09874 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL977495 0.98 XDH (0.61) XDHALDH1A1MAPTMEN1KMT2A
SCHEMBL680148 0.86 XDH (0.63) XDHALDH1A1MAPTMEN1KMT2A
SCHEMBL979252 0.84 KLKB1 (0.65) XDHALDH1A1MAPTMEN1KMT2A
SCHEMBL15006288 0.84 XDH (0.50) XDHALDH1A1MAPTMEN1KMT2A
SCHEMBL5831660 0.83 XDH (0.59) XDHALDH1A1MAPTMEN1KMT2A
SCHEMBL7061099 0.82 XDH (0.48) XDHALDH1A1MAPTMEN1KMT2A
SCHEMBL9273645 0.82 MAPT (0.56) XDHALDH1A1MAPTMEN1KMT2A
Zinc Ion SCHEMBL9246345 0.81 XDH (0.58) XDHALDH1A1MAPTMEN1KMT2A
SCHEMBL9495776 0.81 MEN1 (0.57) XDHALDH1A1MAPTMEN1KMT2A
SCHEMBL5831664 0.81 XDH (0.61) XDHALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5391748-A Recording material BAYER AKTIENGESELLSCHAFT (DE) 1995-02-21 US disclosed