Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PTPRG | P23470 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2164417 | 0.82 | KDM6B (0.61) | KMOPNMTPTPRGTSHR | |
| SCHEMBL2164411 | 0.82 | KDM6B (0.61) | KMOPNMTPTPRGTSHR | |
| SCHEMBL11829343 | 0.82 | CSNK2A1 (0.53) | FFAR1KMT2A | |
| SCHEMBL14844373 | 0.81 | GRIK1 (0.56) | KMOPNMTTAAR1PDPK1PYGL | |
| SCHEMBL14844372 | 0.81 | GRIK1 (0.56) | KMOPNMTTAAR1PDPK1PYGL | |
| SCHEMBL27820206 | 0.80 | PPARG (0.51) | TAAR1FFAR1 | |
| SCHEMBL8595114 | 0.79 | KMT2A (0.54) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9242977 | 0.78 | PDPK1 (0.48) | PNMTTAAR1PDPK1SIGMAR1TMEM97 | |
| SCHEMBL9242982 | 0.77 | TSHR (0.42) | PNMTTAAR1PYGLIGF1RALOX15 | |
| SCHEMBL11828650 | 0.77 | PTGDR2 (0.43) | TAAR1SIGMAR1TMEM97PTGER2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466880-A | Process for preparing ketone enantiomer | PFIZER INC. (US) | 1995-11-14 | — | — | US | claimed |
| EP-0624152-A1 | PROCESS FOR PREPARING KETONE ENANTIOMER. | PFIZER (US) | 1994-11-17 | — | — | EP | claimed |
| WO-1993012062-A1 | PROCESS FOR PREPARING KETONE ENANTIOMER | PFIZER INC. (US) | 1993-06-24 | — | — | WO | claimed |
| US-5466880-A | Process for preparing ketone enantiomer | PFIZER INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5466880-A | Process for preparing ketone enantiomer | PFIZER INC. (US) | 1995-11-14 | — | — | US | disclosed |
| EP-0624152-A1 | PROCESS FOR PREPARING KETONE ENANTIOMER. | PFIZER (US) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993012062-A1 | PROCESS FOR PREPARING KETONE ENANTIOMER | PFIZER INC. (US) | 1993-06-24 | — | — | WO | disclosed |