Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.56 |
| ▸ | KMO | O15229 | 2/20 | 0.54 |
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | PNMT | P11086 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844373 | 1.00 | GRIK1 (0.56) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL16542477 | 0.90 | KMO (0.51) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL28075966 | 0.87 | CA2 (0.54) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL27254709 | 0.83 | KMO (0.48) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL25186421 | 0.83 | GRIA2 (0.48) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL29478421 | 0.83 | SLC7A5 (0.62) | GRIA2KMOKIF11PNMTKCNH2 | |
| SCHEMBL289165 | 0.83 | SLC7A5 (0.62) | GRIA2KMOKIF11PNMTKCNH2 | |
| SCHEMBL43915 | 0.83 | SLC7A5 (0.62) | GRIA2KMOKIF11PNMTKCNH2 | |
| SCHEMBL25186420 | 0.83 | GRIA2 (0.48) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL29397861 | 0.83 | SLC7A5 (0.62) | GRIA2KMOKIF11PNMTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| US-11629171-B2 | Beta-hairpin peptidomimetics | SPEXIS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| CN-115093463-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3201219-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| CN-105324390-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-10-19 | — | — | CN | disclosed |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | SPEXIS AG (CH) | 2021-09-16 | — | — | US | disclosed |
| CN-105849119-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-01-19 | — | — | CN | disclosed |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2020-11-10 | — | — | US | disclosed |
| CN-111770932-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2020-10-13 | — | — | CN | disclosed |
| EP-3707153-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2020-09-16 | — | — | EP | disclosed |
| EP-2764010-B1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2016-03-16 | — | — | EP | disclosed |
| US-20160060298-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-03-03 | — | — | US | disclosed |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-02-25 | — | — | US | disclosed |
| EP-2978771-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978772-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014161782-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014161781-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2014-09-25 | — | — | US | disclosed |
| EP-2764010-A1 | TEMPLATE -FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | Polyphor Ag (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050346-A1 | TEMPLATE -FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | FPR1, FPR3, FPR2 | GRIK1 352/4885GRIK2 1176/4885GRIA1 50/4885 |
| US-20160060298-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, C1S, BACE1 | GRIK1 3485/4885GRIK2 4391/4885GRIA1 2640/4885 |
| US-11629171-B2 | Beta-hairpin peptidomimetics | POLL, POLQ, HBZ | GRIK1 3735/4885GRIK2 4379/4885GRIA1 3982/4885 |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | C1S, POLL, BACE1 | GRIK1 3832/4885GRIK2 4608/4885GRIA1 2838/4885 |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, POLQ, POLM | GRIK1 3951/4885GRIK2 3934/4885GRIA1 4518/4885 |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLQ, POLL, POLM | GRIK1 4041/4885GRIK2 4464/4885GRIA1 4040/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | GRIK1 3418/4885GRIK2 4449/4885GRIA1 2366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.