Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29791623 | 0.88 | PON1 (0.38) | SMN1; SMN2MAPTNPSR1MEN1APAF1 | |
| SCHEMBL925001 | 0.83 | KMT2A (0.46) | BCHEACHESMN1; SMN2MAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL8137482 | 0.81 | KMT2A (0.45) | BCHEACHESMN1; SMN2MAPTNPSR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL2830949 | 0.81 | NPSR1 (0.40) | ACHESMN1; SMN2MAPTNPSR1MEN1 | |
| SCHEMBL29395782 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTNPSR1MEN1APAF1 | |
| SCHEMBL3678674 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTNPSR1MEN1APAF1 | |
| SCHEMBL3675843 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTNPSR1MEN1APAF1 | |
| SCHEMBL29450332 | 0.78 | MEN1 (0.55) | SMN1; SMN2MAPTNPSR1MEN1APAF1 | |
| SCHEMBL625417 | 0.78 | MEN1 (0.55) | SMN1; SMN2MAPTNPSR1MEN1APAF1 | |
| SCHEMBL372352 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTNPSR1MEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252672-B1 | COMPOSITION COMPRISING PHOTOCHROMIC DYES IN AN IONIC SOLVENT | ESSILOR INT (FR) | 2019-02-20 | — | — | EP | claimed |
| US-8411347-B2 | Composition comprising photochromic dyes in an ionic solvent | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2013-04-02 | — | — | US | claimed |
| US-20110013252-A1 | COMPOSITION COMPRISING PHOTOCHROMIC DYES IN AN IONIC SOLVENT | Essilor International (compagnie Generale D'optiqu e (FR) | 2011-01-20 | — | — | US | claimed |
| US-20230374230-A1 | CROSSLINKED GEL FORMULATION | ESSILOR INTERNATIONAL (FR) | 2023-11-23 | — | — | US | disclosed |
| WO-2022078935-A1 | CROSSLINKED GEL FORMULATION | ESSILOR INTERNATIONAL (FR) | 2022-04-21 | — | — | WO | disclosed |
| EP-3985046-A1 | CROSSLINKED GEL FORMULATION | ESSILOR INTERNATIONAL (FR) | 2022-04-20 | — | — | EP | disclosed |
| US-8411347-B2 | Composition comprising photochromic dyes in an ionic solvent | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2013-04-02 | — | — | US | disclosed |
| US-20110013252-A1 | COMPOSITION COMPRISING PHOTOCHROMIC DYES IN AN IONIC SOLVENT | Essilor International (compagnie Generale D'optiqu e (FR) | 2011-01-20 | — | — | US | disclosed |