Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755976 | 0.87 | ABCB1 (0.66) | ABCB1CYP3A4CYP2C9POLBHPGD | |
| SCHEMBL9755937 | 0.85 | ABCB1 (0.60) | ABCB1CYP3A4CYP2C9POLBALDH1A1 | |
| SCHEMBL9756247 | 0.85 | ABCB1 (0.60) | ABCB1CYP3A4CYP2C9POLBHPGD | |
| SCHEMBL9756191 | 0.84 | ABCB1 (0.58) | ABCB1CYP3A4CYP2C9POLBALDH1A1 | |
| SCHEMBL9755881 | 0.84 | ABCB1 (0.58) | ABCB1CYP3A4CYP2C9POLBALDH1A1 | |
| SCHEMBL9755908 | 0.84 | ABCB1 (0.58) | ABCB1CYP3A4CYP2C9POLBALDH1A1 | |
| SCHEMBL10591395 | 0.82 | ABCB1 (0.57) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL10593057 | 0.80 | ABCB1 (0.57) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL9756054 | 0.80 | RAB9A (0.42) | ABCB1CYP3A4CYP2C9TDP1HTT | |
| SCHEMBL8174009 | 0.78 | ABCB1 (0.55) | ABCB1CYP3A4CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347216-A2 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acylhydrazines and N'-substituted -N-acyl-N'-alkylcarbonyl hydrazines | ROHM AND HAAS COMPANY (US) | 1989-12-20 | — | — | EP | claimed |
| US-5424333-A | Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines | ROHM AND HAAS COMPANY (US) | 1995-06-13 | — | — | US | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |