SCHEMBL92467

SCHEMBL92467

CCCOC(=O)c1cc(NC)c2c(c1N)C(=O)c1ccccc1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
MAPT P10636 6/20 0.43
MAPK1 P28482 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
KDM4E B2RXH2 3/20 0.43
THRB P10828 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
GRK6 P43250 1/20 0.43
USP2 O75604 1/20 0.43
PKM P14618 1/20 0.43
MCL1 Q07820 1/20 0.43
TDP1 Q9NUW8 2/20 0.43
GNG2 P59768 1/20 0.42
GNB1 P62873 1/20 0.42
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 2/20 0.41
PDK2 Q15119 1/20 0.40
P2RY4 P51582 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92418 0.91 MAPT (0.47) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL92416 0.85 MAPT (0.50) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL10891401 0.83 ALDH1A1 (0.49) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL11062189 0.80 MAPT (0.67) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL15292716 0.79 MAPT (0.43) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL8572461 0.79 ALDH1A1 (0.58) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL92435 0.77 MAPT (0.47) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL10865030 0.77 ALDH1A1 (0.60) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL10789201 0.77 ALDH1A1 (0.60) ALDH1A1MAPTMAPK1NPSR1KDM4E
SCHEMBL15603988 0.76 ALDH1A1 (0.45) ALDH1A1MAPTMAPK1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129309-B2 Multilayer; substrate with at least three heat sensitive transfer sheets containing dyes and resins, heat resistant slipping layers; containing polyvinyl butyral and polyvinyl acetate FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8119562-B2 Heat-sensitive transfer sheet and image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8067336-B2 Polyethylene innermost surface layer FUJIFILM CORPORATION (JP) 2011-11-29 US disclosed
US-8017552-B2 Has thermal transfer layer on a support, can stably keep up good capability of peeling off an image-receiving sheet without being affected by properties of a support, running stability FUJIFILM CORPORATION (JP) 2011-09-13 US disclosed
US-8012909-B2 Receiver sheet includes receptor layer containing yellow, cyan, magenta dyes; superimposing heat sensitive transfer sheet ; heating; process control FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7879524-B2 Heat sensitive transfer image receiver sheet and heat sensitive transfer sheet on support; dye receiver layer; heat insulation layer containing hollow polymer particles and hydrophilic polymer FUJIFILM CORPORATION (JP) 2011-02-01 US disclosed
US-20080287291-A1 HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080274881-A1 THERMOSENSITIVE TRANSFER INK SHEET, AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080274880-A1 HEAT-SENSITIVE TRANSFER SHEET FOR USE IN HEAT-SENSITIVE TRANSFER SYSTEM AND IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080269048-A1 CARDBOARD CYLINDER FOR A HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET, ROLLED HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET TO FORM A ROLL SHAPE, AND IMAGE-FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-20080254383-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080254981-A1 HEAT-SENSITIVE TRANSFER IMAGE-FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080248949-A1 HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMATION METHOD FUJIFILM CORPORATION (JP) 2008-10-09 US disclosed