SCHEMBL9247751

SCHEMBL9247751

CC(C)(C)c1cc(Cl)c(O)c(C(=O)O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C2 P52895 10/20 0.67
AKR1C1 Q04828 10/20 0.67
AKR1C4 P17516 1/20 0.58
AKR1C3 P42330 1/20 0.58
TTR P02766 1/20 0.44
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
RXRB P28702 1/20 0.42
ACLY P53396 1/20 0.42
CYP2C19 P33261 1/20 0.41
NR1H4 Q96RI1 1/20 0.40
SERPINE1 P05121 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11245202 0.88 AKR1C2 (0.55) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL28717119 0.86 AKR1C2 (0.53) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL9247102 0.83 AKR1C2 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3TTR
SCHEMBL1129780 0.82 AKR1C2 (0.55) AKR1C2AKR1C1AKR1C4AKR1C3TTR
SCHEMBL9247513 0.82 AKR1C2 (0.51) AKR1C2AKR1C1AKR1C4AKR1C3TTR
SCHEMBL11756982 0.81 AKR1C2 (0.49) AKR1C2AKR1C1ALDH1A1HPGDHSD17B10
SCHEMBL3807152 0.81 HMGB1 (0.56) AKR1C2AKR1C1ALDH1A1HPGDHSD17B10
SCHEMBL9740619 0.81 AKR1C2 (0.47) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL14783001 0.80 AKR1C2 (0.47) AKR1C2AKR1C1AKR1C3ALDH1A1TDP1
SCHEMBL6321695 0.80 GABRA1 (0.52) AKR1C2AKR1C1TTRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402380-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2008-07-22 US disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 US disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 US disclosed
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 EP disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed
US-4311758-A INORGANIC PIGMENTS IN THE COLOR DEVELOPER LAYER KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1982-01-19 US disclosed
US-4168845-A Heat-sensitive record material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-09-25 US disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed