Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL29981838 | 1.00 | ALDH1A1 (0.31) | — | |
| Guanidine SCHEMBL15135010 | 0.96 | — | — | |
| Guanidine SCHEMBL31051583 | 0.96 | — | — | |
| Guanidine SCHEMBL4888225 | 0.96 | — | — | |
| Guanidine SCHEMBL15135015 | 0.92 | ALDH1A1 (0.46) | — | |
| Guanidine SCHEMBL28096727 | 0.78 | — | — | |
| Urea SCHEMBL1312661 | 0.76 | — | — | |
| Guanidine SCHEMBL31259153 | 0.75 | — | — | |
| Guanidine SCHEMBL27640020 | 0.75 | — | — | |
| Formic Acid SCHEMBL948333 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12270738-B2 | Fixatives and methods of use | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (MD) | 2025-04-08 | — | — | US | claimed |
| US-20220291094-A1 | FIXATIVES AND METHODS OF USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-09-15 | — | — | US | claimed |
| CN-108602015-B | Fluid for purifying a heat engine using a stable suspension of metal colloidal particles, and method for manufacturing said fluid | IFP新能源公司 | 2021-10-29 | — | — | CN | claimed |
| US-10850233-B2 | Fluid for purifying heat engines using stable suspensions of metal colloidal particles, and methods for preparing said fluid | IFP Energies Nouvelles (FR) | 2020-12-01 | — | — | US | claimed |
| US-10774709-B2 | Fluid for purifying heat engines and methods for preparing said fluids by emulsification | FP ENERGIES NOUVELLES (FR) | 2020-09-15 | — | — | US | claimed |
| US-20180371974-A1 | FLUID FOR PURIFYING HEAT ENGINES AND METHODS FOR PREPARING SAID FLUIDS BY EMULSIFICATION | IFP Energies Nouvelles (FR) | 2018-12-27 | — | — | US | claimed |
| US-20180345216-A1 | FLUID FOR CARRYING OUT POLLUTION CONTROL IN HEAT ENGINES, AND METHODS FOR PREPARING SAID FLUIDS BY PRODUCING A HOMOGENEOUS SOLUTION | IFP Energies Nouvelles (FR) | 2018-12-06 | — | — | US | claimed |
| US-20180304198-A1 | FLUID FOR PURIFYING HEAT ENGINES USING STABLE SUSPENSIONS OF METAL COLLOIDAL PARTICLES, AND METHODS FOR PREPARING SAID FLUID | IFP Energies Nouvelles (FR) | 2018-10-25 | — | — | US | claimed |
| CN-108602015-A | The method that the fluid and the manufacture fluid of Thermal Motor are purified using the stable suspension of metal colloid particle | IFP新能源公司 | 2018-09-28 | — | — | CN | claimed |
| EP-3374063-A1 | FLUID FOR CARRYING OUT POLLUTION CONTROL IN HEAT ENGINES AND METHODS FOR PREPARING SAID FLUIDS BY PRODUCING A HOMOGENEOUS SOLUTION | IFP Energies nouvelles (FR) | 2018-09-19 | — | — | EP | claimed |
| WO-2013110424-A1 | CATALYST FOR THE CONVERSION OF LIQUID AMMONIA PRECURSOR SOLUTIONS TO GASEOUS AMMONIA AVOIDING THE FORMATION OF UNDESIRED SIDE PRODUCTS | PAUL SCHERRER INSTITUT (CH) | 2013-08-01 | — | — | WO | claimed |
| EP-2620213-A1 | Catalyst for the conversion of liquid ammonia precursor solutions to gaseous ammonia avoiding the formation of undesired side products | Paul Scherrer Institut (CH) | 2013-07-31 | — | — | EP | claimed |
| WO-2012104205-A1 | AMMONIA GENERATOR CONVERTING LIQUID AMMONIA PRECURSOR SOLUTIONS TO GASEOUS AMMONIA FOR DENOX-APPLICATIONS USING SELECTIVE CATALYTIC REDUCTION OF NITROGEN OXIDES | PAUL SCHERRER INSTITUT (CH) | 2012-08-09 | — | — | WO | claimed |
| CN-101568372-B | Use of aqueous guanidine formate solutions for the selective catalytic reduction of nitrogen oxides in vehicle exhaust gases | ALZCHEM TROSTBERG GMBH | 2012-02-29 | — | — | CN | claimed |
| CN-101088981-B | Aromatic carboxylic acid producing process | SINOPEC YANGZI PETROCHEMICAL | 2011-03-30 | — | — | CN | claimed |
| EP-2111287-B1 | USE OF AQUEOUS GUANIDINIUM FORMIATE SOLUTIONS FOR THE SELECTIVE CATALYTIC REDUCTION OF NITROGEN OXIDES IN EXHAUST GASES OF VEHICLES | ALZCHEM TROSTBERG GMBH (DE) | 2011-03-09 | — | — | EP | claimed |
| CN-101568372-A | Use of aqueous guanidine formate solutions for the selective catalytic reduction of nitrogen oxides in vehicle exhaust gases | ALZCHEM TROSTBERG GMBH (DE) | 2009-10-28 | — | — | CN | claimed |
| US-20090004128-A1 | Non-Irritant Rapid-Action Dipilatory Composition | PRODUCCIONES INFOVISION (MX) | 2009-01-01 | — | — | US | claimed |
| CN-101088981-A | Aromatic carboxylic acid producing process | YANGZI PETROCHEMICAL CO LTD (CN) | 2007-12-19 | — | — | CN | claimed |
| EP-0030020-B1 | PROCESS FOR THE OBTENTION OF LOW MOLECULAR WEIGHT HYDROCARBONS FROM HIGH MOLECULAR WEIGHT HYDROCARBONS OR FROM COAL | WASAGCHEMIE HOLDING ZUG AG (CH) | 1982-05-19 | — | — | EP | claimed |