Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10372061 | 0.90 | FGFR1 (0.40) | RAB9ANPC1KDM4EHSD17B10MAPT | |
| SCHEMBL10370927 | 0.89 | MAPT (0.36) | KMT2ARAB9ANPC1KDM4EMAPT | |
| SCHEMBL10372642 | 0.85 | NPC1 (0.50) | KMT2ARAB9ANPC1KDM4EMEN1 | |
| SCHEMBL10373632 | 0.85 | RAB9A (0.43) | KMT2ARAB9ANPC1KDM4EMEN1 | |
| SCHEMBL10372062 | 0.84 | BTK (0.37) | KMT2ARAB9ANPC1KDM4EHSD17B10 | |
| SCHEMBL10371048 | 0.81 | NPC1 (0.48) | KMT2ARAB9ANPC1KDM4EMEN1 | |
| SCHEMBL10373929 | 0.80 | JAK2 (0.37) | KMT2ARAB9ANPC1KDM4EMEN1 | |
| SCHEMBL10370990 | 0.79 | KDM4E (0.44) | KMT2ARAB9ANPC1KDM4EMEN1 | |
| SCHEMBL6243266 | 0.78 | GAA (0.43) | KMT2ARAB9ANPC1KDM4EMEN1 | |
| SCHEMBL10373742 | 0.77 | FGFR1 (0.41) | KMT2AMEN1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187487-B1 | BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4703053-A | Benzothiophenes and benzofurans and antiallergic use thereof | WARNER-LAMBERT COMPANY (US) | 1987-10-27 | — | — | US | claimed |
| JP-7149763-A | — | — | None | — | — | JP | disclosed |
| JP-H07149763-A | NOVEL BENZOTHIOPHENE AND BENZOFURAN DERIVATIVES | WARNER LAMBERT CO | 1995-06-13 | — | — | JP | disclosed |
| EP-0187487-B1 | BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4703053-A | Benzothiophenes and benzofurans and antiallergic use thereof | WARNER-LAMBERT COMPANY (US) | 1987-10-27 | — | — | US | disclosed |
| EP-0187487-A1 | Benzothiophenes and benzofurans having antiallergic activity | WARNER-LAMBERT COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |