Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19231275 | 0.98 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHDAO | |
| SCHEMBL20149137 | 0.98 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHDAO | |
| SCHEMBL18499693 | 0.98 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHDAO | |
| SCHEMBL10519887 | 0.94 | MEN1 (0.40) | DAOMEN1KMT2AGAATSHR | |
| SCHEMBL11291118 | 0.84 | CNOT7 (0.41) | DAOCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL16325221 | 0.81 | MAPK10 (0.42) | PTGS1PTGS2MGLLFAAHDAO | |
| SCHEMBL16324726 | 0.81 | MAPK10 (0.42) | PTGS1PTGS2MGLLFAAHDAO | |
| SCHEMBL2048833 | 0.75 | MAPT (0.47) | PTGS1PTGS2MGLLFAAHHTT | |
| SCHEMBL7746318 | 0.74 | PTGS1 (0.46) | PTGS1PTGS2DAOMEN1KMT2A | |
| SCHEMBL4954143 | 0.73 | HTT (0.49) | PTGS1PTGS2MGLLFAAHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039283-C | Use of Porphyrins | FMC CORP (US) | 1998-07-29 | — | — | CN | claimed |
| US-5407808-A | Treating tumor with inhibitor of protoporphyrinogen conversion to heme | FMC CORPORATION (US) | 1995-04-18 | — | — | US | claimed |
| US-5298502-A | Exposure to light in presence of oxidase inhibitor | FMC CORPORATION (US) | 1994-03-29 | — | — | US | claimed |
| EP-0447491-B1 | PROTOPORPHYRINOGEN INHIBITORS AND THEIR USE IN COMPOSITIONS FOR DETECTING AND TREATING TUMOURS | FMC CORP (US) | 1993-08-11 | — | — | EP | claimed |
| US-4767552-A | OIL, FUEL ADDITIVES | THE LUBRIZOL CORPORATION (US) | 1988-08-30 | — | — | US | claimed |
| EP-3010889-B1 | ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-10-03 | — | — | EP | disclosed |
| US-9981928-B2 | Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-29 | — | — | US | disclosed |
| US-20160130240-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | US | disclosed |
| EP-3010889-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014202505-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-12-24 | — | — | WO | disclosed |
| CN-1039283-C | Use of Porphyrins | FMC CORP (US) | 1998-07-29 | — | — | CN | disclosed |
| CN-1171552-A | Use of porphyrins | FMC CORP (US) | 1998-01-28 | — | — | CN | disclosed |
| CN-1057194-A | Preparation and use of porphyrins | FMC CORP (US) | 1991-12-25 | — | — | CN | disclosed |
| US-4767552-A | OIL, FUEL ADDITIVES | THE LUBRIZOL CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| US-4767552-A | OIL, FUEL ADDITIVES | THE LUBRIZOL CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0270662-A1 | URAZOLES COMPOSITIONS USEFUL AS ADDITIVES FOR FUNCTIONAL FLUIDS | The Lubrizol Corporation (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1987007892-A3 | URAZOLES COMPOSITIONS USEFUL AS ADDITIVES FOR FUNCTIONAL FLUIDS | LUBRIZOL CORP (US) | 1988-04-07 | — | — | WO | disclosed |
| WO-1987007892-A2 | URAZOLES COMPOSITIONS USEFUL AS ADDITIVES FOR FUNCTIONAL FLUIDS | THE LUBRIZOL CORPORATION (US) | 1987-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130240-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | ARSA, SQOR, AHR | PTGS1 2050/4885PTGS2 1893/4885MGLL 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.