⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678021 | 0.77 | — | — | |
| SCHEMBL9419494 | 0.75 | — | — | |
| SCHEMBL4825082 | 0.72 | — | — | |
| SCHEMBL11725656 | 0.65 | — | — | |
| SCHEMBL3105985 | 0.62 | — | — | |
| SCHEMBL3235191 | 0.62 | — | — | |
| SCHEMBL9182370 | 0.62 | PTGS2 (0.39) | — | |
| SCHEMBL3429505 | 0.61 | — | — | |
| SCHEMBL140384 | 0.60 | — | — | |
| SCHEMBL23831105 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204964-B1 | 2-PYRROLIDONE DERIVATIVES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | Eisai Co., Ltd. (JP) | 1991-08-28 | — | — | EP | claimed |
| US-5464856-A | Arylmethylenyl derivatives of imidazolidinones useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5306822-A | Mono-, di- or tri-methoxyphenylmethylene-2-thioxo-4-oxazolidinone as antihistamines | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0565135-A1 | Known and selected novel arylmethylenyl derivatives of imidazolidinones useful as antiallergy agents and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| US-5208250-A | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-4892870-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, IMMUNOMODULATING AGENTS | BIOFOR, LTD. (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |