SCHEMBL9248693

SCHEMBL9248693

CC1(C)CCC(OCc2cccc3ccccc23)C(Cc2nc[nH]n2)C1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.36
CNR1 P21554 3/20 0.36
STS P08842 1/20 0.33
CYP2D6 P10635 1/20 0.33
PIN1 Q13526 1/20 0.32
OPRM1 P35372 2/20 0.32
OPRD1 P41143 2/20 0.32
OPRK1 P41145 2/20 0.32
EPHX1 P07099 1/20 0.31
REN P00797 1/20 0.31
BCHE P06276 2/20 0.31
ACHE P22303 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
KCNA5 P22460 1/20 0.30
SCN5A Q14524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244489 0.90 KCNA5 (0.41) CYP2D6KCNA5SCN5A
SCHEMBL9246484 0.83 SLC18A2 (0.39) CNR2CNR1CYP2D6BCHEACHE
SCHEMBL9244512 0.82 CNR2 (0.37) CNR2CNR1STSCYP2D6PIN1
SCHEMBL9244535 0.82 ADRA2A (0.46) CNR2CNR1STSCYP2D6PIN1
SCHEMBL9244528 0.82 ADRA2A (0.46) CNR2CNR1STSCYP2D6PIN1
SCHEMBL8715182 0.81 EPHX1 (0.38) STSOPRM1OPRD1OPRK1EPHX1
SCHEMBL9250038 0.81 EPHX1 (0.38) STSOPRM1OPRD1OPRK1EPHX1
SCHEMBL9248685 0.77 GAA (0.39) CNR2CNR1OPRM1OPRD1OPRK1
SCHEMBL9248690 0.77 GAA (0.39) CNR2CNR1OPRM1OPRD1OPRK1
SCHEMBL9244520 0.75 POLB (0.47) OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5449785-A Fungicides with triazole groups HOFFMANN-LA ROCHE INC. (US) 1995-09-12 US disclosed