SCHEMBL9249396

SCHEMBL9249396

CCc1cc(C(=O)O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.57
GLRA3 O75311 1/20 0.50
GLRB P48167 1/20 0.50
HMGB1 P09429 1/20 0.46
CXCL12 P48061 1/20 0.46
ALDH1A1 P00352 6/20 0.44
KMT2A Q03164 4/20 0.44
TSHR P16473 3/20 0.44
MEN1 O00255 3/20 0.44
MAPK1 P28482 3/20 0.44
MAPT P10636 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
BLM P54132 2/20 0.44
ATM Q13315 2/20 0.44
HIF1A Q16665 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
USP2 O75604 1/20 0.44
CYP2D6 P10635 1/20 0.44
GAA P10253 6/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11778156 0.88 HMGB1 (0.61) HSPA5GLRA3GLRBHMGB1CXCL12
SCHEMBL9769770 0.87 HMGB1 (0.44) HSPA5GLRA3GLRBHMGB1CXCL12
SCHEMBL9250670 0.86 HMGB1 (0.59) HSPA5GLRA3GLRBHMGB1CXCL12
SCHEMBL21585536 0.85 GLRA3 (0.49) HSPA5GLRA3GLRBHMGB1CXCL12
SCHEMBL9249764 0.84 HMGB1 (0.41) HSPA5GLRA3GLRBHMGB1CXCL12
SCHEMBL28090896 0.83 HMGB1 (0.57) HMGB1CXCL12ALDH1A1PTPN1HPGD
SCHEMBL9252477 0.82 PTPN1 (0.42) HSPA5HMGB1CXCL12ALDH1A1KMT2A
SCHEMBL39434 0.81 HSPA5 (0.74) HSPA5ALDH1A1KMT2ATSHRMEN1
SCHEMBL9652211 0.81 PTPN1 (0.63) GLRA3GLRBHMGB1CXCL12KMT2A
SCHEMBL14124050 0.81 HMGB1 (0.76) HSPA5GLRA3GLRBHMGB1CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2602300-B1 PHOTOCHROMIC COMPOSITION TOKUYAMA CORP (JP) 2019-06-12 EP disclosed
US-9234984-B2 Photochromic composition TOKUYAMA CORPORATION (JP) 2016-01-12 US disclosed
US-20130215488-A1 Photochromic Composition TOKUYAMA CORPORATION (JP) 2013-08-22 US disclosed
EP-2602300-A1 PHOTOCHROMIC COMPOSITION Tokuyama Corporation (JP) 2013-06-12 EP disclosed
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 EP disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed
US-3983292-A Pressure sensitive recording papers SANKO CHEMICAL COMPANY LTD. (JA) 1976-09-28 US disclosed