SCHEMBL9769770

SCHEMBL9769770

CCc1cc(C(=O)O)c(O)c(C(C)(C)CC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.44
CXCL12 P48061 1/20 0.44
HSPA5 P11021 1/20 0.42
PTPN1 P18031 5/20 0.40
PTPN2 P17706 2/20 0.36
PTPN6 P29350 2/20 0.36
GLRA3 O75311 1/20 0.36
GLRB P48167 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
KLKB1 P03952 1/20 0.35
CTSB P07858 1/20 0.35
MMP9 P14780 1/20 0.35
DNMT1 P26358 1/20 0.35
DNMT3B Q9UBC3 1/20 0.35
DNMT3L Q9UJW3 1/20 0.35
DNMT3A Q9Y6K1 1/20 0.35
KAT8 Q9H7Z6 2/20 0.35
ALDH1A1 P00352 3/20 0.34
METAP2 P50579 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249764 0.88 HMGB1 (0.41) HMGB1CXCL12HSPA5PTPN1PTPN2
SCHEMBL9249396 0.87 HSPA5 (0.57) HMGB1CXCL12HSPA5PTPN1GLRA3
SCHEMBL9249769 0.84 KAT8 (0.43) HMGB1CXCL12HSPA5PTPN1KAT8
SCHEMBL9652548 0.84 PTPN1 (0.58) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL2070812 0.82 HSPA5 (0.53) HSPA5ALDH1A1HPGDMEN1USP2
SCHEMBL9250721 0.82 ALDH1A1 (0.41) HMGB1CXCL12HSPA5PTPN1GLRA3
SCHEMBL7782928 0.82 RXRA (0.43) HMGB1CXCL12PTPN1GLRA3GLRB
SCHEMBL9166132 0.81 RXRA (0.42) HMGB1CXCL12PTPN1GLRA3GLRB
SCHEMBL9249781 0.81 AKR1C2 (0.51) HMGB1CXCL12GLRA3GLRBALDH1A1
SCHEMBL9501729 0.81 GRIN2D (0.41) HMGB1CXCL12PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed
US-3983292-A Pressure sensitive recording papers SANKO CHEMICAL COMPANY LTD. (JA) 1976-09-28 US disclosed