Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetoacetic Acid SCHEMBL6620 | 0.81 | — | — | |
| Acetoacetic Acid SCHEMBL649090 | 0.81 | LDHA (0.57) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL1144213 | 0.81 | LDHA (0.57) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL1478378 | 0.81 | FFAR3 (0.43) | LMNACYP2D6TSHRCYP2C19HIF1A | |
| Acetoacetic Acid SCHEMBL1406366 | 0.81 | LDHA (0.57) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL28972036 | 0.81 | LDHA (0.57) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL31420005 | 0.81 | — | — | |
| Acetoacetic Acid SCHEMBL10941648 | 0.81 | LDHA (0.57) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL21402364 | 0.81 | — | — | |
| Acetoacetic Acid SCHEMBL653110 | 0.81 | LDHA (0.57) | KDM4EKDM5CEGLN1PHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453464-A | Bis-acetoacetates and bis-beta-ketoesters, crosslinkers for hydroxy containing polymers, films | EASTMAN CHEMICAL COMPANY (US) | 1995-09-26 | — | — | US | disclosed |