Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250100 | 1.00 | USP5 (0.33) | USP5HDAC6CCR2 | |
| SCHEMBL8036593 | 0.99 | USP5 (0.32) | USP5HDAC6CCR2 | |
| SCHEMBL9256069 | 0.93 | CCR2 (0.32) | USP5HDAC6CCR2 | |
| SCHEMBL9256076 | 0.93 | CCR2 (0.32) | USP5HDAC6CCR2 | |
| SCHEMBL8040838 | 0.92 | CCR2 (0.32) | USP5HDAC6CCR2 | |
| SCHEMBL8040836 | 0.92 | CCR2 (0.32) | USP5HDAC6CCR2 | |
| SCHEMBL8040843 | 0.92 | CCR2 (0.32) | USP5HDAC6CCR2 | |
| SCHEMBL8036643 | 0.91 | — | — | |
| SCHEMBL8036636 | 0.91 | — | — | |
| SCHEMBL8036641 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0315014-B1 | Halogenated benzene derivatives | HOFFMANN LA ROCHE (CH) | 1994-01-12 | — | — | EP | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |